Cortico-Calm Matrix with Relora / Relora配方抗压平衡补充剂

产品描述

Cortico-Calm Matrix 旨在帮助皮质醇释放增多或皮质醇分泌过早并因此出现睡眠问题的人。该配方含有专利草本提取物和支持性营养素，有助于降低皮质醇水平，并在压力或不规则皮质醇模式期间平息过度活跃的神经系统。

长期以来，人们都知道不规则的皮质醇分泌会对一系列健康指标产生负面影响，包括睡眠、认知、代谢功能和免疫力。在理想状态下，皮质醇在醒来时释放，水平在一天中逐渐下降，然后在休息和睡眠周期中降至最低。现代生活方式和外部压力源并不总是允许这种健康的皮质醇曲线。在某些情况下，皮质醇分泌过多或过早，晚上的分泌水平更高。

Cortico-Calm Matrix 含有 Relora®，这是两种草药提取物（厚朴和黄柏）的专利混合物，经过临床研究和数十年的实际应用，可将其用于控制​​皮质醇水平。临床试验表明，Relora® 可以主观地减轻压力、改善睡眠质量、降低皮质醇水平、减少对高糖食物的渴望，并保持压力饮食者的体重。一项试验发现，轻度至中度压力的个体仅服用 2 周补充剂，唾液皮质醇水平就会下降 37%，唾液脱氢表雄酮 (DHEA) 会显著增加。这些效果似乎是由于活性成分厚朴酚和和厚朴酚与 GABA 受体结合所致。

另一种用于支持健康皮质醇水平和压力相关问题的强效植物是印度醉茄，俗称南非醉茄。

Cortico-Calm Matrix 包含一种名为 Sensoril® 南非醉茄的专利提取物，经过十几项临床试验，支持人类健康和压力反应的多个方面。具体而言，它已被证明可以增加能量、降低皮质醇水平、抑制对食物的渴望、改善认知、提高运动表现并减少运动恢复时间。服用 Sensoril® 的个人发现，压力管理方面有主观改善，报告称烦躁减少、注意力提高和疲劳减少。Sensoril® 也有证据表明，根据高灵敏度 C 反应蛋白测量，它可以减少炎症，并减轻膝盖不适患者的关节疼痛。它标准化为 3 种生物活性成分，即醉茄内酯糖苷、醉茄素 A 和寡糖，以确保一致的质量和效果。这两种专利草本提取物都与 Cortico-Calm Matrix 中的支持性营养素相结合，以优化皮质醇反应并镇静神经系统。

这些重要营养素之一是磷脂酰丝氨酸。磷脂酰丝氨酸是大脑中的主要磷脂之一，参与中枢神经系统内的细胞间通讯。研究发现，它有助于调节多种神经递质，包括乙酰胆碱、去甲肾上腺素、血清素和多巴胺，十多项研究发现，它在学习、记忆、注意力和回忆等认知领域有显著改善。研究还发现，在过度运动的情况下，磷脂酰胆碱可以降低皮质醇，并且具有极高的安全性。

最后，Cortico-Calm Matrix 还添加了γ-氨基丁酸 (GABA)、镁和肌醇，可协同作用于升高的压力反应。GABA 是人类大脑中的主要抑制性神经递质，负责在兴奋条件下平静心灵和平衡神经传递。研究表明，补充 GABA 可以改善压力期间的放松和注意力，减少睡眠潜伏期并增加深度睡眠时间。同样，镁对于维持正常的神经和肌肉功能必不可少，但也是线粒体中产生细胞能量以及作为构建 DNA、RNA 和许多蛋白质的辅助因子所必需的。镁以高度稳定且生物可利用的双甘氨酸盐形式存在。肌醇与磷脂酰丝氨酸一样，是细胞膜的关键成分。肌醇通过增加细胞受体的敏感性，在调节细胞之间的通讯和信号传导方面发挥着关键作用。事实证明，它可以增加血清素、乙酰胆碱、去甲肾上腺素、胰岛素和甲状腺激素的受体敏感性。总的来说，这 3 种支持性营养素的机制都表明压力反应减少且更加平衡。

特点：

Relora®、南非醉茄、磷脂酰丝氨酸和支持性营养素的混合物，可降低皮质醇并镇静神经系统

• 旨在降低皮质醇水平并减少持续压力的相关症状
• Relora® 是厚朴和黄檗的专有混合物，研究显示它能够降低皮质醇水平、改善睡眠质量并减少对食物的渴望
• Sensoril® 南非醉茄也被证明可以降低皮质醇水平并抑制对食物的渴望，同时还可以降低炎症标志物、疲劳和运动恢复时间
• 磷脂酰丝氨酸不仅可以降低皮质醇水平，而且还是大脑中的主要磷脂，有助于调节神经递质和支持认知
• GABA、镁和肌醇被添加以镇静神经系统、支持睡眠和调节神经递质水平

成分：

以上计量单位：每粒胶囊

成分 数量
GABA（γ-氨基丁酸） 100mg
Sensoril® 南非醉茄（根和叶，Withania somnifera）5:1，312.5mg DHE，32% 南非醉茄寡糖，10% 醉茄内酯糖苷，0.05% 醉茄素 A* 62.5mg
肌醇 50mg
Relora®**
厚朴提取物（树枝皮，厚朴） 8.5% 厚朴酚 34.37mg
黄柏提取物（树枝皮，Phellodendron amurense） 2.5% 小檗碱 11.25mg
磷脂酰丝氨酸(种子，向日葵) 25 毫克
镁 (Albion™ 镁双甘氨酸螯合物)*** 25 毫克

使用说明和注意事项

适应症：

Cortico-Calm Matrix 有助于降低皮质醇和 C 反应蛋白水平（身体压力的生物标志物），并有助于暂时促进放松。它有助于减轻压力症状，如疲劳、失眠、易怒和注意力不集中。

使用说明：

成人 - 每天服用 2 粒胶囊或按照医疗保健专业人员的指示服用。

使用期限：

如果使用超过 6 周，请咨询医疗保健专业人员。

注意事项：

使用前请咨询医疗保健专业人员，尤其是如果您正在服用任何处方药、患有肾脏疾病或有血压问题。如果您患有任何心理障碍和/或疾病，如频繁焦虑或抑郁，请在使用前咨询医疗保健专业人员。与具有镇静作用的草药、补充剂和药物同时使用可能会增加过度嗜睡的风险。如果症状持续或恶化，请咨询医疗保健专业人员。可能导致胃灼热、手抖、阴唇周围麻木、性功能障碍和甲状腺功能障碍。如果密封破损，请勿使用。请放在儿童接触不到的地方。

禁忌症：

如果您正在怀孕或哺乳，请勿使用。不建议与酒精、其他药物或具有镇静和/或止痛作用的天然保健产品一起服用。

已知不良反应：

有些人可能会感到嗜睡。如果操作重型机械、驾驶机动车或参与需要精神警觉的活动，请小心谨慎。

Product Description

Cortico-Calm Matrix is designed to support individuals with an elevated cortisol release or those with untimely cortisol production and subsequent sleep concerns. This formula contains patented herbal extracts and supportive nutrients to help lower cortisol levels and calm an overactive nervous system during times of stress or irregular cortisol patterns. 

Irregular cortisol output has long been known to negatively impact a wide array of health measures including sleep, cognition, metabolic function, and immunity. In an ideal state, cortisol is released upon waking and levels gradually decline throughout the day before bottoming out during rest and sleep cycles. Modern lifestyles and external stressors do not always allow for this healthy cortisol curve. In certain cases, cortisol production is excessive or untimely with greater output levels in the evening. 

Cortico-Calm Matrix contains Relora® a patented blend of two herbal extracts, Magnolia officinalis and Phellodendron amurense, with clinical research and decades of practical application to support its use for managing cortisol levels. Clinical trials have shown that Relora® can subjectively reduce stress, improve sleep quality, reduce cortisol levels, decrease cravings for high-sugar foods, and maintain weight in stress-eaters. One trial found that just 2 weeks of supplementation in mild to moderately stressed individuals led to a 37% decrease in salivary cortisol levels and a significant increase in salivary DHEA. These effects appear to be due to the active ingredients magnolol and honokiol binding to GABA receptors.

Another powerful plant used to support healthy cortisol levels and stress-related concerns is Withania somnifera, more commonly known as ashwagandha. 

Cortico-Calm Matrix includes a patented extract known as Sensoril® ashwagandha with a dozen clinical trials to support multiple aspects of human health and the stress response. Specifically, it has been shown to increase energy, reduce cortisol levels, suppress food cravings, improve cognition, improve athletic performance, and reduce exercise recovery time. Individuals taking Sensoril® find subjective improvements in stress management by reporting less irritability, improved concentration, and reduced fatigue. Sensoril® also has evidence to show that it can reduce inflammation, as per high-sensitivity C-reactive protein measurements, and reduce joint pain in those with knee discomfort. It is standardized to 3 bioactive ingredients, withanolide glycosides, withaferin A, and oligosaccharides, to ensure consistent quality and results. Both of these patented herbal extracts have been combined with supportive nutrients in Cortico-Calm Matrix to optimize the cortisol response and calm the nervous system.

One of these important nutrients is phosphatidylserine. Phosphatidylserine is one of the major phospholipids found in the brain and is involved in cell-to-cell communication within the central nervous system. Studies have found that it can help to regulate multiple neurotransmitters, including acetylcholine, norepinephrine, serotonin, and dopamine, with more than a dozen studies finding significant improvements in areas of cognition such as learning, memory, concentration, and recall. Phosphatidylcholine has also been found to lower cortisol in cases of excess physical exercise and has demonstrated an extremely high safety profile.

Finally, Cortico-Calm Matrix includes added gamma-aminobutyric acid (GABA), magnesium, and myo-inositol to act synergistically on an elevated stress response. GABA  is the major inhibitory neurotransmitter found in the human brain and it is responsible for calming the mind and balancing neurotransmission under excitatory conditions. Studies indicate that GABA supplementation can improve relaxation and concentration during times of stress, reduce sleep latency and increase time spent in deep sleep. Similarly, magnesium is necessary for maintaining proper nerve and muscle function, but also needed to create cellular energy in the mitochondria and as a cofactor to build DNA, RNA, and many proteins. Magnesium is delivered in its highly stable and bioavailable bis-glycinate form. Inositol, like phosphatidylserine, is a key component of the cellular membrane. Inositol is key in regulating communication and signaling between cells by increasing the sensitivity of cell receptors. It has been demonstrated to increase receptor sensitivity for serotonin, acetylcholine, norepinephrine, insulin and thyroid hormones. Collectively, the mechanisms of these 3 supportive nutrients all indicate a reduced and more balanced stress response. 

Features:

Ingredients:

Unit of Measure above: Each capsule

Directions & Cautions

Indications:

Cortico-Calm Matrix helps to reduce cortisol and C-reactive protein levels, the biomarkers of physical stress, and helps to temporarily promote relaxation. It helps reduce the symptoms of stress, such as fatigue, sleeplessness, irritability, and inability to concentrate.

Directions for Use:

Adults - Take 2 capsules per day or as directed by a healthcare professional.

Duration of use:

Consult a healthcare professional for use beyond 6 weeks.

Cautions:

Consult a healthcare professional prior to use, especially if you are taking any prescription medication, if you have a kidney disorder, or if you have blood pressure problems. Consult a healthcare professional prior to use if you suffer from any psychological disorder and/or condition such as frequent anxiety or depression. Concomitant use with herbs, supplements and medications that have sedative properties might increase the risk of excessive drowsiness. Consult a healthcare professional if symptoms persist or worsen. May cause heartburn, shaking hands, perilabial numbness, sexual dysfunction and thyroid dysfunction. Do not use if seal is broken. Keep out of reach of children.

Contraindications:

Do not use if you are pregnant or breastfeeding. Consumption with alcohol, other medications or natural health products with sedative and/or analgesic properties is not recommended.

Known Adverse Reactions:

Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. 

*These statements have not been evaluated by the Food and Drug Administration. This product is not in tended to diagnose, treat, cure, or prevent any disease. 
Some formulas may be slightly different outside Canada and the US.